Creating centimeter-scale complex tissue geometries within seconds via Volumetric Bioprinting

Our finite ability to spontaneously regenerate our organs, associated with increasing longevity, reinforces the need for engineered human tissues. Bioprinting made constructing architecturally complex, centimeter-scale 3D living structures possible in hours, arranging cells and materials into pattern that can hasten maturation into functional tissues. Nevertheless, biological elements such as cells and biomolecules are sensitive to physical stimuli and have shortened lifetime in solution. This can result in the reduction of cell function proportionally to printing time.

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The emergence of 4D Bioprinting: Next Generation in regenerative medicine & human-machine interfacing

Stephen Gray

An overview of the 4D bioprinting industry and its potential impact on regenerative medicine and human-machine interfaces to diagnose, monitor and treat a wide range of diseases. Novel emerging biofabrication technologies and biomaterials with superior advantages such as nanoscale resolution & cells reaching high viability whilst maintaining metabolic and pluripotent characteristics.

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3D printing of scaffolds and biomolecules for enhanced tissue repair

Tissue engineering typically uses a combination of biomaterial scaffolds, cells and signaling mechanisms (such as growth factors or mechanical stimuli) to restore the function of damaged or degenerated tissues. The research carried out in our laboratory investigates each of these three areas with target applications in tissues including bone, cartilage, skin, cardiovascular, respiratory, and neural tissues. 3D printing has allowed us to tune the mechanical properties of our scaffolds and to develop bioinks with enhanced regenerative potential.

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From Scaffold Design to Control Stem Cell Fate to Bioprinting

lorenzo moroni

Organs are complex systems, comprised of different tissues, proteins, and cells, which communicate to orchestrate a myriad of functions in our bodies. Technologies are needed to replicate these structures towards the development of new therapies for tissue and organ repair, as well as for in vitro 3D models to better understand the morphogenetic biological processes that drive organogenesis.

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